Proteomics Analysis of Amyloid and Nonamyloid Prion Disease Phenotypes Reveals Both Common and Divergent Mechanisms of Neuropathogenesis

[Image: see text] Prion diseases are a heterogeneous group of neurodegenerative disorders affecting various mammals including humans. Prion diseases are characterized by a misfolding of the host-encoded prion protein (PrP(C)) into a pathological isoform termed PrP(Sc). In wild-type mice, PrP(C) is a...

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Detalles Bibliográficos
Autores principales: Moore, Roger A., Sturdevant, Dan E., Chesebro, Bruce, Priola, Suzette A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227561/
https://www.ncbi.nlm.nih.gov/pubmed/25140793
http://dx.doi.org/10.1021/pr500329w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227561/
https://www.ncbi.nlm.nih.gov/pubmed/25140793
http://dx.doi.org/10.1021/pr500329w

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