Cargando…

Targeted Proteomic Quantitation of the Absolute Expression and Turnover of Cystic Fibrosis Transmembrane Conductance Regulator in the Apical Plasma Membrane

[Image: see text] Deficient chloride transport through cystic fibrosis (CF) transmembrane conductance regulator (CFTR) causes lethal complications in CF patients. CF is the most common autosomal recessive genetic disease, which is caused by mutations in the CFTR gene; thus, CFTR mutants can serve as...

Descripción completa

Detalles Bibliográficos
Autores principales: McShane, Adam J., Bajrami, Bekim, Ramos, Alex A., Diego-Limpin, Pamela A., Farrokhi, Vahid, Coutermarsh, Bonita A., Stanton, Bruce A., Jensen, Tim, Riordan, John R., Wetmore, Diana, Joseloff, Elizabeth, Yao, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227562/
https://www.ncbi.nlm.nih.gov/pubmed/25227318
http://dx.doi.org/10.1021/pr5006795