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Analysis of ANK3 and CACNA1C variants identified in bipolar disorder whole genome sequence data

OBJECTIVES: Genetic markers in the genes encoding ankyrin 3 (ANK3) and the α-calcium channel subunit (CACNA1C) are associated with bipolar disorder (BP). The associated variants in the CACNA1C gene are mainly within intron 3 of the gene. ANK3 BP-associated variants are in two distinct clusters at th...

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Detalles Bibliográficos
Autores principales: Fiorentino, Alessia, O'Brien, Niamh Louise, Locke, Devin Paul, McQuillin, Andrew, Jarram, Alexandra, Anjorin, Adebayo, Kandaswamy, Radhika, Curtis, David, Blizard, Robert Alan, Gurling, Hugh Malcolm Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227602/
https://www.ncbi.nlm.nih.gov/pubmed/24716743
http://dx.doi.org/10.1111/bdi.12203