Thermodynamic System Drift in Protein Evolution

Proteins from thermophiles are generally more thermostable than their mesophilic homologs, but little is known about the evolutionary process driving these differences. Here we attempt to understand how the diverse thermostabilities of bacterial ribonuclease H1 (RNH) proteins evolved. RNH proteins f...

Descripción completa

Detalles Bibliográficos
Autores principales: Hart, Kathryn M., Harms, Michael J., Schmidt, Bryan H., Elya, Carolyn, Thornton, Joseph W., Marqusee, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227636/
https://www.ncbi.nlm.nih.gov/pubmed/25386647
http://dx.doi.org/10.1371/journal.pbio.1001994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227636/
https://www.ncbi.nlm.nih.gov/pubmed/25386647
http://dx.doi.org/10.1371/journal.pbio.1001994

Ejemplares similares