miR-107 Activates ATR/Chk1 Pathway and Suppress Cervical Cancer Invasion by Targeting MCL1

MicroRNAs (miRNAs) are a class of single-stranded, non-coding RNAs of about 22 nucleotides in length. Increasing evidence implicates miRNAs may function as oncogenes or tumor suppressors. Here we showed that miR-107 directly targeted MCL1 and activated ATR/Chk1 pathway to inhibit proliferation, migr...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Chengyan, Li, Gang, Zhou, Jingjing, Han, Na, Liu, Zhihui, Yin, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227659/
https://www.ncbi.nlm.nih.gov/pubmed/25386925
http://dx.doi.org/10.1371/journal.pone.0111860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227659/
https://www.ncbi.nlm.nih.gov/pubmed/25386925
http://dx.doi.org/10.1371/journal.pone.0111860

Ejemplares similares