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Modulating the Structure of EGFR with UV Light: New Possibilities in Cancer Therapy
The epidermal growth factor receptor (EGFR) is a member of the ErbB family of receptor tyrosine kinases. EGFR is activated upon binding to e.g. epidermal growth factor (EGF), leading to cell survival, proliferation and migration. EGFR overactivation is associated with tumor progression. We have prev...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227675/ https://www.ncbi.nlm.nih.gov/pubmed/25386651 http://dx.doi.org/10.1371/journal.pone.0111617 |