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Modulating the Structure of EGFR with UV Light: New Possibilities in Cancer Therapy

The epidermal growth factor receptor (EGFR) is a member of the ErbB family of receptor tyrosine kinases. EGFR is activated upon binding to e.g. epidermal growth factor (EGF), leading to cell survival, proliferation and migration. EGFR overactivation is associated with tumor progression. We have prev...

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Detalles Bibliográficos
Autores principales: Correia, Manuel, Thiagarajan, Viruthachalam, Coutinho, Isabel, Gajula, Gnana Prakash, Petersen, Steffen B., Neves-Petersen, Maria Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227675/
https://www.ncbi.nlm.nih.gov/pubmed/25386651
http://dx.doi.org/10.1371/journal.pone.0111617