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Hypoxic Conditioned Medium from Rat Cerebral Cortical Cells Enhances the Proliferation and Differentiation of Neural Stem Cells Mainly through PI3-K/Akt Pathways

PURPOSE: To investigate the effects of hypoxic conditioned media from rat cerebral cortical cells on the proliferation and differentiation of neural stem cells (NSCs) in vitro, and to study the roles of PI3-K/Akt and JNK signal transduction pathways in these processes. METHODS: Cerebral cortical cel...

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Detalles Bibliográficos
Autores principales: Cai, Ming, Zhou, Yuehui, Zhou, Bin, Lou, Shujie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227679/
https://www.ncbi.nlm.nih.gov/pubmed/25386685
http://dx.doi.org/10.1371/journal.pone.0111938