Cargando…

Mosaicism of Podocyte Involvement Is Related to Podocyte Injury in Females with Fabry Disease

BACKGROUND: Fabry disease. an X-linked deficiency of α-galactosidase A coded by the GLA gene, leads to intracellular globotriaosylceramide (GL-3) accumulation. Although less common than in males, chronic kidney disease, occurs in ∼15% of females. Recent studies highlight the importance of podocyte i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mauer, Michael, Glynn, Emily, Svarstad, Einar, Tøndel, Camilla, Gubler, Marie-Claire, West, Michael, Sokolovskiy, Alexey, Whitley, Chester, Najafian, Behzad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227696/ https://www.ncbi.nlm.nih.gov/pubmed/25386848 http://dx.doi.org/10.1371/journal.pone.0112188

Ejemplares similares

One Year of Enzyme Replacement Therapy Reduces Globotriaosylceramide Inclusions in Podocytes in Male Adult Patients with Fabry Disease
por: Najafian, Behzad, et al.
Publicado: (2016)

Reduction of podocyte globotriaosylceramide content in adult male patients with Fabry disease with amenable GLA mutations following 6 months of migalastat treatment
por: Mauer, Michael, et al.
Publicado: (2017)

Urinary Podocyte Loss Is Increased in Patients with Fabry Disease and Correlates with Clinical Severity of Fabry Nephropathy
por: Fall, Brent, et al.
Publicado: (2016)

Accumulation of α-synuclein mediates podocyte injury in Fabry nephropathy
por: Braun, Fabian, et al.
Publicado: (2023)

Dysregulated Autophagy Contributes to Podocyte Damage in Fabry’s Disease
por: Liebau, Max C., et al.
Publicado: (2013)

Early decrease in the podocalyxin to synaptopodin ratio in urinary Fabry podocytes
por: Trimarchi, Hernán, et al.
Publicado: (2018)

Expression of uPAR in Urinary Podocytes of Patients with Fabry Disease
por: Trimarchi, Hernán, et al.
Publicado: (2017)

The phenotypes of podocytes and parietal epithelial cells may overlap in diabetic nephropathy
por: Andeen, Nicole K., et al.
Publicado: (2015)

Podocytes
por: Reiser, Jochen, et al.
Publicado: (2016)

Receptor-Mediated Endocytosis of α-Galactosidase A in Human Podocytes in Fabry Disease
por: Prabakaran, Thaneas, et al.
Publicado: (2011)

Endothelin and the podocyte
por: Barton, Matthias, et al.
Publicado: (2012)

Gene Expression Analysis in gla-Mutant Zebrafish Reveals Enhanced Ca(2+) Signaling Similar to Fabry Disease
por: Elsaid, Hassan Osman Alhassan, et al.
Publicado: (2022)

Proteomic analysis unveils Gb3-independent alterations and mitochondrial dysfunction in a gla(−/−) zebrafish model of Fabry disease
por: Elsaid, Hassan Osman Alhassan, et al.
Publicado: (2023)

Mechanisms and consequences of TGF-ß overexpression by podocytes in progressive podocyte disease
por: Lee, Hyun Soon
Publicado: (2011)

Role of the podocyte in proteinuria
por: Menzel, Sylvia, et al.
Publicado: (2011)

Insulin in podocyte podiatry
por: Makino, Yuichi, et al.
Publicado: (2011)

Podocytes … What’s Under Yours? (Podocytes and Foot Processes and How They Change in Nephropathy)
por: Neal, Chris R.
Publicado: (2015)

The Role of Podocytes and Podocyte-Associated Biomarkers in Diagnosis and Treatment of Diabetic Kidney Disease
por: Kravets, Igor, et al.
Publicado: (2020)

Podocyte-Specific Deletion of Murine CXADR Does Not Impair Podocyte Development, Function or Stress Response
por: Schell, Christoph, et al.
Publicado: (2015)

IQGAP1 Interacts with Components of the Slit Diaphragm Complex in Podocytes and Is Involved in Podocyte Migration and Permeability In Vitro
por: Rigothier, Claire, et al.
Publicado: (2012)

A multicolor podocyte reporter highlights heterogeneous podocyte changes in focal segmental glomerulosclerosis
por: Tao, Jianling, et al.
Publicado: (2013)

Peroxidase expression is decreased by palmitate in cultured podocytes but increased in podocytes of advanced diabetic nephropathy
por: Lee, Eugene, et al.
Publicado: (2018)

Preterm birth leads to a decreased number of differentiated podocytes and accelerated podocyte differentiation
por: Zhang, Lulu, et al.
Publicado: (2023)

Reduced α-galactosidase A activity in zebrafish (Danio rerio) mirrors distinct features of Fabry nephropathy phenotype
por: Elsaid, Hassan O.A., et al.
Publicado: (2022)

α-Galactosidase a Deficiency in Fabry Disease Leads to Extensive Dysregulated Cellular Signaling Pathways in Human Podocytes
por: Jehn, Ulrich, et al.
Publicado: (2021)

Membranous nephropathy without vacuolated podocytes in Fabry disease treated with agalsidase-β and carbamazepine: A case report
por: Kanai, Takahiro, et al.
Publicado: (2022)

Podocyte Mitosis – A Catastrophe
por: Lasagni, L, et al.
Publicado: (2013)

Nuclear hormone receptors in podocytes
por: Khurana, Simran, et al.
Publicado: (2012)

The podocyte cytoskeleton in health and in disease
por: Mathieson, Peter W.
Publicado: (2012)

Editorial: Podocyte Pathology and Nephropathy
por: Lewko, Barbara, et al.
Publicado: (2015)

Non-muscle myosins and the podocyte
por: Noris, Marina, et al.
Publicado: (2012)

The Podocyte in Diabetic Kidney Disease
por: Stitt-Cavanagh, Erin, et al.
Publicado: (2009)

Regulation of the Actin Cytoskeleton in Podocytes
por: Blaine, Judith, et al.
Publicado: (2020)

Podocyte Injury in Lupus Nephritis
por: Sakhi, Hamza, et al.
Publicado: (2019)

Role of Podocyte Injury in Glomerulosclerosis
por: Lu, Chen-Chen, et al.
Publicado: (2019)

Gangliosides in Podocyte Biology and Disease
por: Savas, Berkan, et al.
Publicado: (2020)

Podocyte Autophagy in Homeostasis and Disease
por: Lin, Qisheng, et al.
Publicado: (2021)

Ligation of α-Dystroglycan on Podocytes Induces Intracellular Signaling: A New Mechanism for Podocyte Effacement?
por: Vogtländer, Nils P. J., et al.
Publicado: (2009)

Diabetes Induced Changes in Podocyte Morphology and Gene Expression Evaluated Using GFP Transgenic Podocytes
por: Xu, Jianxiang, et al.
Publicado: (2016)

C/EBPα deficiency in podocytes aggravates podocyte senescence and kidney injury in aging mice
por: Zhang, Liwen, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_5d8ql312hil62efd2oal5lr6og