Mosaicism of Podocyte Involvement Is Related to Podocyte Injury in Females with Fabry Disease
BACKGROUND: Fabry disease. an X-linked deficiency of α-galactosidase A coded by the GLA gene, leads to intracellular globotriaosylceramide (GL-3) accumulation. Although less common than in males, chronic kidney disease, occurs in ∼15% of females. Recent studies highlight the importance of podocyte i...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227696/ https://www.ncbi.nlm.nih.gov/pubmed/25386848 http://dx.doi.org/10.1371/journal.pone.0112188 |