Urinary Podocyte Loss Is Increased in Patients with Fabry Disease and Correlates with Clinical Severity of Fabry Nephropathy

Chronic kidney disease is a major complication of Fabry disease. Podocytes accumulate globotriaosylceramide inclusions more than other kidney cell types in Fabry patients. Podocyte injury occurs early in age, and is progressive. Since injured podocytes detach into the urine (podocyturia), we hypothe...

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Detalles Bibliográficos
Autores principales: Fall, Brent, Scott, C. Ronald, Mauer, Michael, Shankland, Stuart, Pippin, Jeffrey, Jefferson, Jonathan A., Wallace, Eric, Warnock, David, Najafian, Behzad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161377/
https://www.ncbi.nlm.nih.gov/pubmed/27992580
http://dx.doi.org/10.1371/journal.pone.0168346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161377/
https://www.ncbi.nlm.nih.gov/pubmed/27992580
http://dx.doi.org/10.1371/journal.pone.0168346

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