Poly(Ethylene Glycol) as a Scaffold for High-Affinity Open-Channel Blockers of the Mouse Nicotinic Acetylcholine Receptor

High-affinity blockers for an ion channel often have complex molecular structures that are synthetically challenging and/or laborious. Here we show that high-affinity blockers for the mouse nicotinic acetylcholine receptor (AChR) can be prepared from a structurally simple material, poly(ethylene gly...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Wan-Chen, Licht, Stuart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227698/
https://www.ncbi.nlm.nih.gov/pubmed/25386750
http://dx.doi.org/10.1371/journal.pone.0112088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227698/
https://www.ncbi.nlm.nih.gov/pubmed/25386750
http://dx.doi.org/10.1371/journal.pone.0112088

Ejemplares similares