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PIM Kinases as Potential Therapeutic Targets in a Subset of Peripheral T Cell Lymphoma Cases

Currently, there is no efficient therapy for patients with peripheral T cell lymphoma (PTCL). The Proviral Integration site of Moloney murine leukemia virus (PIM) kinases are important mediators of cell survival. We aimed to determine the therapeutic value of PIM kinases because they are overexpress...

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Detalles Bibliográficos
Autores principales: Martín-Sánchez, Esperanza, Odqvist, Lina, Rodríguez-Pinilla, Socorro M., Sánchez-Beato, Margarita, Roncador, Giovanna, Domínguez-González, Beatriz, Blanco-Aparicio, Carmen, García Collazo, Ana M., Cantalapiedra, Esther González, Fernández, Joaquín Pastor, del Olmo, Soraya Curiel, Pisonero, Helena, Madureira, Rebeca, Almaraz, Carmen, Mollejo, Manuela, Alves, F. Javier, Menárguez, Javier, González-Palacios, Fernando, Rodríguez-Peralto, José Luis, Ortiz-Romero, Pablo L., Real, Francisco X., García, Juan F., Bischoff, James R., Piris, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227704/
https://www.ncbi.nlm.nih.gov/pubmed/25386922
http://dx.doi.org/10.1371/journal.pone.0112148