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Conformational Changes Associated with Post-Translational Modifications of Pro(143) in Skp1 of Dictyostelium—A Dipeptide Model System
[Image: see text] Prolyl hydroxylation and subsequent glycosylation of the E3(SCF) ubiquitin ligase subunit Skp1 affects its conformation and its interaction with F-box proteins and, ultimately, O(2)-sensing in the organism. Taking a reductionist approach to understand the molecular basis for these...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227711/ https://www.ncbi.nlm.nih.gov/pubmed/25250945 http://dx.doi.org/10.1021/ja5033277 |