Conformational Changes Associated with Post-Translational Modifications of Pro(143) in Skp1 of Dictyostelium—A Dipeptide Model System

[Image: see text] Prolyl hydroxylation and subsequent glycosylation of the E3(SCF) ubiquitin ligase subunit Skp1 affects its conformation and its interaction with F-box proteins and, ultimately, O(2)-sensing in the organism. Taking a reductionist approach to understand the molecular basis for these...

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Detalles Bibliográficos
Autores principales: Karunaratne, Chamini V., Weldeghiorghis, Thomas K., West, Christopher M., Taylor, Carol M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227711/
https://www.ncbi.nlm.nih.gov/pubmed/25250945
http://dx.doi.org/10.1021/ja5033277

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