Enzyme-Controlled Nitrogen-Atom Transfer Enables Regiodivergent C–H Amination

[Image: see text] We recently demonstrated that variants of cytochrome P450(BM3) (CYP102A1) catalyze the insertion of nitrogen species into benzylic C–H bonds to form new C–N bonds. An outstanding challenge in the field of C–H amination is catalyst-controlled regioselectivity. Here, we report two en...

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Detalles Bibliográficos
Autores principales: Hyster, Todd K., Farwell, Christopher C., Buller, Andrew R., McIntosh, John A., Arnold, Frances H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227740/
https://www.ncbi.nlm.nih.gov/pubmed/25325618
http://dx.doi.org/10.1021/ja509308v

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227740/
https://www.ncbi.nlm.nih.gov/pubmed/25325618
http://dx.doi.org/10.1021/ja509308v

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