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HIV-2 genomic RNA accumulates in stress granules in the absence of active translation

During the post-transcriptional events of the HIV-2 replication cycle, the full-length unspliced genomic RNA (gRNA) is first used as an mRNA to synthesize Gag and Gag-Pol proteins and then packaged into progeny virions. However, the mechanisms responsible for the coordinate usage of the gRNA during...

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Detalles Bibliográficos
Autores principales: Soto-Rifo, Ricardo, Valiente-Echeverria, Fernando, Rubilar, Paulina S., Garcia-de-Gracia, Francisco, Ricci, Emiliano P., Limousin, Taran, Décimo, Didier, Mouland, Andrew J., Ohlmann, Théophile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227750/
https://www.ncbi.nlm.nih.gov/pubmed/25352557
http://dx.doi.org/10.1093/nar/gku1017