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Why base tautomerization does not cause errors in mRNA decoding on the ribosome

The structure of the genetic code implies strict Watson–Crick base pairing in the first two codon positions, while the third position is known to be degenerate, thus allowing wobble base pairing. Recent crystal structures of near-cognate tRNAs accommodated into the ribosomal A-site, however, show ca...

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Detalles Bibliográficos
Autores principales: Satpati, Priyadarshi, Åqvist, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227757/
https://www.ncbi.nlm.nih.gov/pubmed/25352546
http://dx.doi.org/10.1093/nar/gku1044