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SNP-guided identification of monoallelic DNA-methylation events from enrichment-based sequencing data

Monoallelic gene expression is typically initiated early in the development of an organism. Dysregulation of monoallelic gene expression has already been linked to several non-Mendelian inherited genetic disorders. In humans, DNA-methylation is deemed to be an important regulator of monoallelic gene...

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Detalles Bibliográficos
Autores principales: Steyaert, Sandra, Van Criekinge, Wim, De Paepe, Ayla, Denil, Simon, Mensaert, Klaas, Vandepitte, Katrien, Berghe, Wim Vanden, Trooskens, Geert, De Meyer, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227762/
https://www.ncbi.nlm.nih.gov/pubmed/25237057
http://dx.doi.org/10.1093/nar/gku847