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A real-time fluorescence polarization activity assay to screen for inhibitors of bacterial ribonuclease P

Ribonuclease P (RNase P) is an essential endonuclease that catalyzes the 5′ end maturation of precursor tRNA (pre-tRNA). Bacterial RNase P is an attractive potential antibacterial target because it is essential for cell survival and has a distinct subunit composition compared to the eukaryal counter...

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Detalles Bibliográficos
Autores principales:	Liu, Xin, Chen, Yu, Fierke, Carol A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227764/ https://www.ncbi.nlm.nih.gov/pubmed/25249623 http://dx.doi.org/10.1093/nar/gku850

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