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Critical role of DNA intercalation in enzyme-catalyzed nucleotide flipping
Nucleotide flipping is a common feature of DNA-modifying enzymes that allows access to target sites within duplex DNA. Structural studies have identified many intercalating amino acid side chains in a wide variety of enzymes, but the functional contribution of these intercalating residues is poorly...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227769/ https://www.ncbi.nlm.nih.gov/pubmed/25324304 http://dx.doi.org/10.1093/nar/gku919 |