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Critical role of DNA intercalation in enzyme-catalyzed nucleotide flipping

Nucleotide flipping is a common feature of DNA-modifying enzymes that allows access to target sites within duplex DNA. Structural studies have identified many intercalating amino acid side chains in a wide variety of enzymes, but the functional contribution of these intercalating residues is poorly...

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Detalles Bibliográficos
Autores principales:	Hendershot, Jenna M., O'Brien, Patrick J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227769/ https://www.ncbi.nlm.nih.gov/pubmed/25324304 http://dx.doi.org/10.1093/nar/gku919

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