Potential non-B DNA regions in the human genome are associated with higher rates of nucleotide mutation and expression variation

While individual non-B DNA structures have been shown to impact gene expression, their broad regulatory role remains elusive. We utilized genomic variants and expression quantitative trait loci (eQTL) data to analyze genome-wide variation propensities of potential non-B DNA regions and their relatio...

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Detalles Bibliográficos
Autores principales: Du, Xiangjun, Gertz, E. Michael, Wojtowicz, Damian, Zhabinskaya, Dina, Levens, David, Benham, Craig J., Schäffer, Alejandro A., Przytycka, Teresa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227770/
https://www.ncbi.nlm.nih.gov/pubmed/25336616
http://dx.doi.org/10.1093/nar/gku921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227770/
https://www.ncbi.nlm.nih.gov/pubmed/25336616
http://dx.doi.org/10.1093/nar/gku921

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