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Potential non-B DNA regions in the human genome are associated with higher rates of nucleotide mutation and expression variation
While individual non-B DNA structures have been shown to impact gene expression, their broad regulatory role remains elusive. We utilized genomic variants and expression quantitative trait loci (eQTL) data to analyze genome-wide variation propensities of potential non-B DNA regions and their relatio...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227770/ https://www.ncbi.nlm.nih.gov/pubmed/25336616 http://dx.doi.org/10.1093/nar/gku921 |