Search by proteins for their DNA target site: 2. The effect of DNA conformation on the dynamics of multidomain proteins

Multidomain transcription factors, which are especially abundant in eukaryotic genomes, are advantageous to accelerate the search kinetics for target site because they can follow the intersegment transfer via the monkey-bar mechanism in which the protein forms a bridged intermediate between two dist...

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Detalles Bibliográficos
Autores principales: Bhattacherjee, Arnab, Levy, Yaakov
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227779/
https://www.ncbi.nlm.nih.gov/pubmed/25324311
http://dx.doi.org/10.1093/nar/gku933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227779/
https://www.ncbi.nlm.nih.gov/pubmed/25324311
http://dx.doi.org/10.1093/nar/gku933

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