Suppression of subtelomeric VSG switching by Trypanosoma brucei TRF requires its TTAGGG repeat-binding activity

Trypanosoma brucei causes human African trypanosomiasis and regularly switches its major surface antigen, VSG, in the bloodstream of its mammalian host to evade the host immune response. VSGs are expressed exclusively from subtelomeric loci, and we have previously shown that telomere proteins TbTIF2...

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Detalles Bibliográficos
Autores principales: Jehi, Sanaa E., Li, Xiaohua, Sandhu, Ranjodh, Ye, Fei, Benmerzouga, Imaan, Zhang, Mingjie, Zhao, Yanxiang, Li, Bibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227783/
https://www.ncbi.nlm.nih.gov/pubmed/25313155
http://dx.doi.org/10.1093/nar/gku942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227783/
https://www.ncbi.nlm.nih.gov/pubmed/25313155
http://dx.doi.org/10.1093/nar/gku942

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