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Identification of a Mg(2+)-sensitive ORF in the 5′-leader of TRPM7 magnesium channel mRNA

TRPM7 is an essential and ubiquitous channel-kinase regulating cellular influx of Mg(2+). Although TRPM7 mRNA is highly abundant, very small amount of the protein is detected in cells, suggesting post-transcriptional regulation of trpm7 gene expression. We found that TRPM7 mRNA 5′-leader contains tw...

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Detalles Bibliográficos
Autores principales: Nikonorova, Inna A., Kornakov, Nikolay V., Dmitriev, Sergey E., Vassilenko, Konstantin S., Ryazanov, Alexey G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227784/
https://www.ncbi.nlm.nih.gov/pubmed/25326319
http://dx.doi.org/10.1093/nar/gku951