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Architecture and ssDNA interaction of the Timeless-Tipin-RPA complex

The Timeless-Tipin (Tim-Tipin) complex, also referred to as the fork protection complex, is involved in coordination of DNA replication. Tim-Tipin is suggested to be recruited to replication forks via Replication Protein A (RPA) but details of the interaction are unknown. Here, using cryo-EM and bio...

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Detalles Bibliográficos
Autores principales: Witosch, Justine, Wolf, Eva, Mizuno, Naoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227788/
https://www.ncbi.nlm.nih.gov/pubmed/25348395
http://dx.doi.org/10.1093/nar/gku960