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G-quadruplexes in viruses: function and potential therapeutic applications

G-rich nucleic acids can form non-canonical G-quadruplex structures (G4s) in which four guanines fold in a planar arrangement through Hoogsteen hydrogen bonds. Although many biochemical and structural studies have focused on DNA sequences containing successive, adjacent guanines that spontaneously f...

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Detalles Bibliográficos
Autores principales: Métifiot, Mathieu, Amrane, Samir, Litvak, Simon, Andreola, Marie-Line
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227801/
https://www.ncbi.nlm.nih.gov/pubmed/25332402
http://dx.doi.org/10.1093/nar/gku999