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Ginsenoside Rb1 Prevents H(2)O(2)-Induced HUVEC Senescence by Stimulating Sirtuin-1 Pathway

PURPOSES: We have previously reported that Ginsenoside Rb1 may effectively prevent HUVECs from senescence, however, the detailed mechanism has not demonstrated up to now. Recent studies have shown that sirtuin-1 (Sirt1) plays an important role in the development of endothelial senescence. The purpos...

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Detalles Bibliográficos
Autores principales: Song, Zhiming, Liu, Yong, Hao, Baoshun, Yu, Shujie, Zhang, Hui, Liu, Dinghui, Zhou, Bin, Wu, Lin, Wang, Min, Xiong, Zhaojun, Wu, Chaodong, Zhu, Jieming, Qian, Xiaoxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227851/
https://www.ncbi.nlm.nih.gov/pubmed/25386949
http://dx.doi.org/10.1371/journal.pone.0112699