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Phosphoproteome Profiling of the Macrophage Response to Different Toll-Like Receptor Ligands Identifies Differences in Global Phosphorylation Dynamics

[Image: see text] Toll-like receptors (TLRs) are among the first sensors that detect infection and drive immune response. Macrophages encountering a pathogen are usually stimulated not by one TLR, but by a combination of TLRs engaged by distinct microbe ligands. To understand the integrated signalin...

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Detalles Bibliográficos
Autores principales: Sjoelund, Virginie, Smelkinson, Margery, Nita-Lazar, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227906/
https://www.ncbi.nlm.nih.gov/pubmed/24941444
http://dx.doi.org/10.1021/pr5002466