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Phosphoproteome Profiling of the Macrophage Response to Different Toll-Like Receptor Ligands Identifies Differences in Global Phosphorylation Dynamics
[Image: see text] Toll-like receptors (TLRs) are among the first sensors that detect infection and drive immune response. Macrophages encountering a pathogen are usually stimulated not by one TLR, but by a combination of TLRs engaged by distinct microbe ligands. To understand the integrated signalin...
Autores principales: | Sjoelund, Virginie, Smelkinson, Margery, Nita-Lazar, Aleksandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227906/ https://www.ncbi.nlm.nih.gov/pubmed/24941444 http://dx.doi.org/10.1021/pr5002466 |
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