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PrimPol Bypasses UV Photoproducts during Eukaryotic Chromosomal DNA Replication
DNA damage can stall the DNA replication machinery, leading to genomic instability. Thus, numerous mechanisms exist to complete genome duplication in the absence of a pristine DNA template, but identification of the enzymes involved remains incomplete. Here, we establish that Primase-Polymerase (Pri...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228047/ https://www.ncbi.nlm.nih.gov/pubmed/24267451 http://dx.doi.org/10.1016/j.molcel.2013.10.035 |