PrimPol Bypasses UV Photoproducts during Eukaryotic Chromosomal DNA Replication

DNA damage can stall the DNA replication machinery, leading to genomic instability. Thus, numerous mechanisms exist to complete genome duplication in the absence of a pristine DNA template, but identification of the enzymes involved remains incomplete. Here, we establish that Primase-Polymerase (Pri...

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Detalles Bibliográficos
Autores principales: Bianchi, Julie, Rudd, Sean G., Jozwiakowski, Stanislaw K., Bailey, Laura J., Soura, Violetta, Taylor, Elaine, Stevanovic, Irena, Green, Andrew J., Stracker, Travis H., Lindsay, Howard D., Doherty, Aidan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Short Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228047/
https://www.ncbi.nlm.nih.gov/pubmed/24267451
http://dx.doi.org/10.1016/j.molcel.2013.10.035

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