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A Conserved Oct4/POUV-Dependent Network Links Adhesion and Migration to Progenitor Maintenance

BACKGROUND: The class V POU domain transcription factor Oct4 (Pou5f1) is a pivotal regulator of embryonic stem cell (ESC) self-renewal and reprogramming of somatic cells to induced pluripotent stem (iPS) cells. Oct4 is also an important evolutionarily conserved regulator of progenitor cell different...

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Detalles Bibliográficos
Autores principales: Livigni, Alessandra, Peradziryi, Hanna, Sharov, Alexei A., Chia, Gloryn, Hammachi, Fella, Migueles, Rosa Portero, Sukparangsi, Woranop, Pernagallo, Salvatore, Bradley, Mark, Nichols, Jennifer, Ko, Minoru S.H., Brickman, Joshua M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228055/
https://www.ncbi.nlm.nih.gov/pubmed/24210613
http://dx.doi.org/10.1016/j.cub.2013.09.048