Identification of the angiogenic gene signature induced by EGF and hypoxia in colorectal cancer

BACKGROUND: Colorectal cancer (CRC) is characterised by hypoxia, which activates gene transcription through hypoxia-inducible factors (HIF), as well as by expression of epidermal growth factor (EGF) and EGF receptors, targeting of which has been demonstrated to provide therapeutic benefit in CRC. Al...

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Detalles Bibliográficos
Autores principales: Khong, Tak L, Thairu, Ngayu, Larsen, Helene, Dawson, Peter M, Kiriakidis, Serafim, Paleolog, Ewa M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228238/
https://www.ncbi.nlm.nih.gov/pubmed/24180698
http://dx.doi.org/10.1186/1471-2407-13-518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228238/
https://www.ncbi.nlm.nih.gov/pubmed/24180698
http://dx.doi.org/10.1186/1471-2407-13-518

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