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Genetic variants in ADAM33 are associated with airway inflammation and lung function in COPD

BACKGROUND: Genetic factors play a role in the development and severity of chronic obstructive pulmonary disease (COPD). The pathogenesis of COPD is a multifactorial process including an inflammatory cell profile. Recent studies revealed that single nucleotide polymorphisms (SNPs) within ADAM33 incr...

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Detalles Bibliográficos
Autores principales: Wang, Xinyan, Li, Wan, Huang, Kun, Kang, Xiaowen, Li, Zhaoguo, Yang, Chengcheng, Wu, Xiaomei, Chen, Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228268/
https://www.ncbi.nlm.nih.gov/pubmed/25369941
http://dx.doi.org/10.1186/1471-2466-14-173