PGRN protects against colitis progression in mice in an IL-10 and TNFR2 dependent manner

This study was aimed to determine the role and regulation of progranulin (PGRN) in the pathogenesis of inflammatory bowel diseases (IBD). Dextran sulfate sodium (DSS)−, picrylsulfonic acid (TNBS)-induced, bone marrow chimera and CD4+CD45Rb(hi) T cell transfer colitis model were established and analy...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Fanhua, Zhang, Yuying, Jian, Jinlong, Mundra, Jyoti Joshi, Tian, Qingyun, Lin, Jiqiang, Lafaille, Juan Jose, Tang, Wei, Zhao, Weiming, Yu, Xiuping, Liu, Chuan-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228332/
https://www.ncbi.nlm.nih.gov/pubmed/25387791
http://dx.doi.org/10.1038/srep07023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228332/
https://www.ncbi.nlm.nih.gov/pubmed/25387791
http://dx.doi.org/10.1038/srep07023

Ejemplares similares