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RhoA and Membrane Fluidity Mediates the Spatially Polarized Src/FAK Activation in Response to Shear Stress

While Src plays crucial roles in shear stress-induced cellular processes, little is known on the spatiotemporal pattern of high shear stress (HSS)-induced Src activation. HSS (65 dyn/cm(2)) was applied on bovine aortic endothelial cells to visualize the dynamic Src activation at subcellular levels u...

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Detalles Bibliográficos
Autores principales: Liu, Bo, Lu, Shaoying, Hu, Ying-li, Liao, Xiaoling, Ouyang, Mingxing, Wang, Yingxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228346/
https://www.ncbi.nlm.nih.gov/pubmed/25387906
http://dx.doi.org/10.1038/srep07008