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RhoA and Membrane Fluidity Mediates the Spatially Polarized Src/FAK Activation in Response to Shear Stress
While Src plays crucial roles in shear stress-induced cellular processes, little is known on the spatiotemporal pattern of high shear stress (HSS)-induced Src activation. HSS (65 dyn/cm(2)) was applied on bovine aortic endothelial cells to visualize the dynamic Src activation at subcellular levels u...
Autores principales: | Liu, Bo, Lu, Shaoying, Hu, Ying-li, Liao, Xiaoling, Ouyang, Mingxing, Wang, Yingxiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228346/ https://www.ncbi.nlm.nih.gov/pubmed/25387906 http://dx.doi.org/10.1038/srep07008 |
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