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Identification of direction in gene networks from expression and methylation
BACKGROUND: Reverse-engineering gene regulatory networks from expression data is difficult, especially without temporal measurements or interventional experiments. In particular, the causal direction of an edge is generally not statistically identifiable, i.e., cannot be inferred as a statistical pa...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228359/ https://www.ncbi.nlm.nih.gov/pubmed/24182195 http://dx.doi.org/10.1186/1752-0509-7-118 |