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Identification of direction in gene networks from expression and methylation

BACKGROUND: Reverse-engineering gene regulatory networks from expression data is difficult, especially without temporal measurements or interventional experiments. In particular, the causal direction of an edge is generally not statistically identifiable, i.e., cannot be inferred as a statistical pa...

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Detalles Bibliográficos
Autores principales: Simcha, David M, Younes, Laurent, Aryee, Martin J, Geman, Donald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228359/
https://www.ncbi.nlm.nih.gov/pubmed/24182195
http://dx.doi.org/10.1186/1752-0509-7-118