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Functional conservation of HIV-1 Gag: implications for rational drug design
BACKGROUND: HIV-1 replication can be successfully blocked by targeting gag gene products, offering a promising strategy for new drug classes that complement current HIV-1 treatment options. However, naturally occurring polymorphisms at drug binding sites can severely compromise HIV-1 susceptibility...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228425/ https://www.ncbi.nlm.nih.gov/pubmed/24176092 http://dx.doi.org/10.1186/1742-4690-10-126 |