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Integration of multiscale dendritic spine structure and function data into systems biology models

Comprising 10(11) neurons with 10(14) synaptic connections the human brain is the ultimate systems biology puzzle. An increasing body of evidence highlights the observation that changes in brain function, both normal and pathological, consistently correlate with dynamic changes in neuronal anatomy....

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Detalles Bibliográficos
Autores principales: Mancuso, James J., Cheng, Jie, Yin, Zheng, Gilliam, Jared C., Xia, Xiaofeng, Li, Xuping, Wong, Stephen T. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228840/
https://www.ncbi.nlm.nih.gov/pubmed/25429262
http://dx.doi.org/10.3389/fnana.2014.00130