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Defying c-Abl signaling circuits through small allosteric compounds
Many extracellular and intracellular signals promote the c-Abl tyrosine kinase activity. c-Abl in turn triggers a multitude of changes either in protein phosphorylation or in gene expression in the cell. Yet, c-Abl takes part in diverse signaling routes because of several domains linked to its catal...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228975/ https://www.ncbi.nlm.nih.gov/pubmed/25429298 http://dx.doi.org/10.3389/fgene.2014.00392 |