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Targeted Delivery of Anticancer Agents via a Dual Function Nanocarrier with an Interfacial Drug-Interactive Motif

[Image: see text] We have developed a dual-function drug carrier, polyethylene glycol (PEG)-derivatized farnesylthiosalicylate (FTS). Here we report that incorporation of a drug-interactive motif (Fmoc) into PEG(5k)–FTS(2) led to further improvement in both drug loading capacity and formulation stab...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaolan, Huang, Yixian, Zhao, Wenchen, Liu, Hao, Marquez, Rebecca, Lu, Jianqin, Zhang, Peng, Zhang, Yifei, Li, Jiang, Gao, Xiang, Venkataramanan, Raman, Xu, Liang, Li, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229023/
https://www.ncbi.nlm.nih.gov/pubmed/25325795
http://dx.doi.org/10.1021/bm501339j