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Ensemble-Based Network Aggregation Improves the Accuracy of Gene Network Reconstruction

Reverse engineering approaches to constructing gene regulatory networks (GRNs) based on genome-wide mRNA expression data have led to significant biological findings, such as the discovery of novel drug targets. However, the reliability of the reconstructed GRNs needs to be improved. Here, we propose...

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Detalles Bibliográficos
Autores principales: Zhong, Rui, Allen, Jeffrey D., Xiao, Guanghua, Xie, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229114/
https://www.ncbi.nlm.nih.gov/pubmed/25390635
http://dx.doi.org/10.1371/journal.pone.0106319