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Ensemble-Based Network Aggregation Improves the Accuracy of Gene Network Reconstruction
Reverse engineering approaches to constructing gene regulatory networks (GRNs) based on genome-wide mRNA expression data have led to significant biological findings, such as the discovery of novel drug targets. However, the reliability of the reconstructed GRNs needs to be improved. Here, we propose...
Autores principales: | Zhong, Rui, Allen, Jeffrey D., Xiao, Guanghua, Xie, Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229114/ https://www.ncbi.nlm.nih.gov/pubmed/25390635 http://dx.doi.org/10.1371/journal.pone.0106319 |
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