Eupatorin-Induced Cell Death in Human Leukemia Cells Is Dependent on Caspases and Activates the Mitogen-Activated Protein Kinase Pathway

Eupatorin is a naturally occurring flavone that inhibits cell proliferation in human tumor cells. Here we demonstrate that eupatorin arrests cells at the G(2)-M phase of the cell cycle and induces apoptotic cell death involving activation of multiple caspases, mitochondrial release of cytochrome c a...

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Detalles Bibliográficos
Autores principales: Estévez, Sara, Marrero, María Teresa, Quintana, José, Estévez, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229185/
https://www.ncbi.nlm.nih.gov/pubmed/25390937
http://dx.doi.org/10.1371/journal.pone.0112536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229185/
https://www.ncbi.nlm.nih.gov/pubmed/25390937
http://dx.doi.org/10.1371/journal.pone.0112536

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