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Comparative Analysis of Human γD-Crystallin Aggregation under Physiological and Low pH Conditions

Cataract, a major cause of visual impairment worldwide, is the opacification of the eye’s crystalline lens due to aggregation of the crystallin proteins. The research reported here is aimed at investigating the aggregating behavior of γ-crystallin proteins in various incubation conditions. Thioflavi...

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Detalles Bibliográficos
Autores principales: Wu, Josephine W., Chen, Mei-Er, Wen, Wen-Sing, Chen, Wei-An, Li, Chien-Ting, Chang, Chih-Kai, Lo, Chun-Hsien, Liu, Hwai-Shen, Wang, Steven S.-S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229192/
https://www.ncbi.nlm.nih.gov/pubmed/25389780
http://dx.doi.org/10.1371/journal.pone.0112309