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Accelerated Recovery of Mitochondrial Membrane Potential by GSK-3β Inactivation Affords Cardiomyocytes Protection from Oxidant-Induced Necrosis

Loss of mitochondrial membrane potential (ΔΨ(m)) is known to be closely linked to cell death by various insults. However, whether acceleration of the ΔΨ(m) recovery process prevents cell necrosis remains unclear. Here we examined the hypothesis that facilitated recovery of ΔΨ(m) contributes to cytop...

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Detalles Bibliográficos
Autores principales: Sunaga, Daisuke, Tanno, Masaya, Kuno, Atsushi, Ishikawa, Satoko, Ogasawara, Makoto, Yano, Toshiyuki, Miki, Takayuki, Miura, Tetsuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229200/
https://www.ncbi.nlm.nih.gov/pubmed/25390651
http://dx.doi.org/10.1371/journal.pone.0112529