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Non-Invasive MRI and Spectroscopy of mdx Mice Reveal Temporal Changes in Dystrophic Muscle Imaging and in Energy Deficits

In Duchenne muscular dystrophy (DMD), a genetic disruption of dystrophin protein expression results in repeated muscle injury and chronic inflammation. Magnetic resonance imaging shows promise as a surrogate outcome measure in both DMD and rehabilitation medicine that is capable of predicting clinic...

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Detalles Bibliográficos
Autores principales: Heier, Christopher R., Guerron, Alfredo D., Korotcov, Alexandru, Lin, Stephen, Gordish-Dressman, Heather, Fricke, Stanley, Sze, Raymond W., Hoffman, Eric P., Wang, Paul, Nagaraju, Kanneboyina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229202/
https://www.ncbi.nlm.nih.gov/pubmed/25390038
http://dx.doi.org/10.1371/journal.pone.0112477